I had a smooth bore side by side with 26" tubes, front and rear sights, that I could keep 2 rights and 2 lefts on a 10" square steel gong at 100 meters, offhand.
The powder charge was 190gr. of 2F GOEX which produced 1,550fps. It kicked pretty hard and was not even remotely pleasant to shoot. 191gr. is 7 drams.
This was almost good enough for deer, but not quite. It would have been fine for moose or elk, under perfect conditions, which rarely exist when hunting so-
no smoothbore, however sighted, is in my opinion OK for deer at 100yards.
I would still draw the limit at 50yards, bush hunting, whether sighted or not.
One of our guys won a smoothbore event by hitting all of the 150yard gongs.
Before the match, we had a discussion about longer range smoothbore targets at the range.
I told him to double his powder charge for the long targets, which he did, to 140gr. 2F, in his 20 bore.
He said he'd held on the top edge of the gongs and hit every one in the middle, bit left, right, high or low
but hit them all and was the only one to do that.
Everyone else stayed with their normal 65 to 75gr. 2F loads.