Am I the only one that H A T E S the straight flute Track of the Wolf ramrod drill? Squalls, gets tight, it's horrible. Oh, and it most definitely can go off. A great deal. I've had better success (though hardly 100%) with the "Brad tip" drill I got from Muzzleloader Builders Supply some time ago.
There is no gunsmithing task I dread more, or curse more than drilling ramrod holes.
I've been shooting for about 1/8" of "web" at the breech end of the barrel. Now, since the muzzle is thinner, if you made the hole parallel to the bore, the "web" at the muzzle will be larger, depending upon the muzzle size. Sometimes this would make for an overly thick-looking "web" at the muzzle with an octagon to round barrel, where the muzzle is usually fairly small. So, in order to keep it from having such a huge space between the barrel and rod at the muzzle, you can lay out the rod slightly tapered, a little closer to the bore center at the muzzle. Only a little, though. If the fore end is tapered too much, it will look horrible. You just have to work it all out with what you've got. I might have 1/8" of "web" at the rear, but 3/16" or 1/4", or even 5/16" at the front with a narrow-muzzled octagon to round barrel.
I have never had a gun drill run off unless AIMED wrong or care is not taken is starting it. I just drilled a hole for a class at our guild meeting in maybe 5-8 minutes with my Dewalt and it ran just as aimed, again. But if the rod CHANNEL that guides the drill is off 1/32 or worse from end to end it will be multiplied at the end of the hole. The rod groove needs be parallel with bore centerline in all respects unless the barrel is straight sided. Otherwise strange things can happen. Also use is Ivory soap to lube the shaft of the drill.
If the drill binds and the hole is straight there are a couple of fixes. I make my own, the one I used a couple of weeks back was made from mild steel rod case hardened after it was grooved and shaped. Its possible to burnish a slight burr on the cutting edge side of the groove to make it cut just a little larger so the shaft has a little clearance if needed. Its also possible to flex the shaft slightly and cause the drill, especially a twist version that is more than a couple of inches long in the flutes to run off, since the twist portion will easily flex and can cut aggressively on the side of the hole behind the point.
If the gun drill shaft is flexed by the weight of the drill motor or the users hand or body misalignment at the start it may not start straight, and this will cause binding and run out of the hole even with a gun drill. If one end of the rod is pressed down it will tend to force the other end down as the shaft is flexed since its prevented from moving by the blocks holding it in the groove.
Dan