Today's rounded bottom rifling requires a thicker patch with any ball chosen as the rifling depth averages about .006" DEEPER than rifling with what is referred to as square rifling.
Thus, the patch SHOULD be at least .003"to .005" thicker than what you would use standard square rifling or .010" to .012" depth.
For example, if you normally use .010", you'd need .013" to .015" in the rounded rifling, if you get my drift.
Also, a ball that is only .005" smaller than the bore would also be best to use in either type of rifling.
Taylor's .50 Virginia rifle has .016" deep rounded rifling. He uses a .495" ball and a .022" patch. Up to 85gr of 2F, this patch holds. Any load over that and the patches get burn lines due to the blowby in the grooves. Thus, for a more accurate load for heavier loads, he needs a thicker patch due to the rounded rifling.
In square rifling, the .022" patch will withstand ANY load, including his 200yard load which was well over 100gr. I just can't remember what that was. I'll probably wake up at 3AM tonight and declare to no one in particular, 115gr. 2F GOEX- or something like that!
I was just kidding about the .010" to .015" patches - they are even too thin for a handkerchief - in other words, useless - in my opinion.
You have to fill the grooves to the bottom + have some compression of the ball itself- cloth marks on the ball from each and every groove.
Rounded grooves usually clean easier than square - is noted by many people. However, if you use a load as noted above, there is no buildup of fouling in the corners of the grooves and the square rifling cleans very well. All of my rifles have square rifling - they all clean up with one patch for pumping water in and out and 3 to 5 for drying and oiling.
If you are interested in competitions - even trail walks, you might be better off with square rifling .010" to .012" deep. No serious match shooters use rounded grooves - wonder why?