Taylor has been shooting more 3F in his .50's - due mostly I think, to running out of 2F. Years ago I spend considerable range time testing 2F against 3F and found in all rifles tested (.50's and larger), 2F gave better accuracy and LESS fouling. 3f is hotter, as in developing higher pressure and velocity for any given load, yes. As it develops higher pressure, it's demands on a tight patch are even more severe.
I've tested 3F in all my guns up to & including the .69 and although even 3F shot fairly well, I could not exceed 95gr. or I got burnt patches - I was using .022" commercial patches then.(I later found out they were only .018" according to my measurements. This barrel has since shown it prefers tighter patches than the 10 ounce denim) That 95gr. 3F load produced 1,350fps. With 2F, I could run all the way to 165gr. and 1,550fps and not burn those same patches and with that load & .030" patches, the very best accuracy was achieved grossly surpassing 3F at 100 to 300yards.
I did not develop 2f loads for my .32, however the .40 and .45 both shot equally, accuracy and velocity wise, once I raised the powder charge by 10gr. for the slower powder.
Since I recently sold both .40 and .45, but bought a new .50 as well as rebarreling the .32 to .36, I now have 2 "new" calibres to test - with both 2f and 3F.