i'd start by asking meself, what do i wanna use this gun for? this will come down to loose or tight loads, or maybe somewhere in between. there is no way to guess what yer gun wants to be fed, for the tasks you'll ask it to do, unless you spend the time testing loads. that means trialing a few different diameter balls, more than a few different patch thicknesses and material types, maybe some different lubes - and then there's the powder itself, from its brand and granulation to its load down the tube. ain't dis stuff fun?
quick 'n' easy .45 starter testing is 3f powder and an adjustable measure, a .440 ball, some patch material in .010, .015 and .018 thicknesses, spit for patch lube, and have at it.