An archival problem is census records don't show names of household members until 1850. Plus (oddly) Carlisle isn't listed in any family trees in the LDS database, so we don't have his wife's or children's names to crossreference.
In 1820 Henry Carlisle (abt 1787-1847) had 3 persons in his household, with only he and his wife as adults, and one person (himself) engaged in manufacturing.
By 1830 Carlisle had 8 persons in his Shippensburg household with 4 of them adults. That means he had employees and probably apprentices.
In 1840 the numbers increase to 9 with 5 adults. And in 1849 Carlisle died.
But John H. Johnston (1811-1889), gunsmith, is present with 100% certainty.
In 1850 he's a gunsmith in Waynesboro with $1000 in assets.
Ditto 1860 with $2100 in assets....$3300 in 1870....and he died in 1889. He and his wife Rachel had 7 children, 4 of them boys, but as they came of age in the cartridge era I didn't pursue them. His son Joseph was educated in an unspecified university in the 1860's, so Johnston was doing fairly well.