Back in the day the 50 caliber was considered the minimum for western use by the fur companies.
While I have little doubt a 50 will kill an elk well with good shot placement. But my experience with a 54 tells me that 62 is probably ideal. I walked to within 20 yards of a cow elk with the 16 bore but was about 2 miles too far south to shoot a cow
Nice soft snow... Would not grow horns no matter how I looked at her. Pre-wolves cows were legal at that spot
Anyway I didn't get to try the 16 on elk, so far.
This is the shoulder blade of a mule deer doe. 495 rb, 90 gr fff, 60 yards. Ball when exactly where it was pointed but not where the sights were, one of "those things". Operator error but I would have bet things were OK.
Anyway ball struck the socket of the shoulder blade
Did this in the chest cavity
And exited the offside.
So the 50 will even handle deer sized bone fairly well though it likely would not had exited had it struck the end of the humerus.
its a great deer caliber, decent power and easy recoil shoots very flat with this load. Can hold dead on to about 130 yards.
But this said a friend shot a deer at 120 yards with a 45 broke a rib on entry and exit.
Dan