I am from p.a, an have shot many years with my 45 cal flinter/rifle with 84 gr/3f/.445rb. I bet i have killed easily 20 deer, at range's from 10yds to 90yrds,with none flopping over on the spot, with good heart/lung shots. They almost always run off like they were missed an are flopped over within 50yds in a matter of 30seconds. I went to a 58 cal hawkin rifle to knock-em-stiff on the spot, only to find out that the 58cal makes better blood trails an bigger holes but in all truth, they still run about 40-50 yrds an pile up. I then tried a 54 cal for the faster-optimum size hunting ball i read about. Nope! same thing.......heck!, i hit one with my car an it ran 30yrds an fell over. The only dead on arrival rb shot,is the brain, or the spine.....sorry! there is no magic size, just magic spots to hit them.....sonny