I leave them with what seems to be a factory .052" vent, except for the pistol with the little John Bailes lock- that one gets opened to 1/16". They burn all the way out to .070" quickly enough if left alone, let along hastening the process.
By all means, if your ignition is sketchy, opening them to 1/16" to start is the way to go.
At first, I opened them to .070" but that's too big in my opinion and doesn't take long before, if set at 1/2 cock, frizzen closed then loaded, will just about self-prime completely if using 3F. Powder is srayed out that large a vent as the ball is seated and the air from inside the barrel tries to blow all the powder out the only opening, the vent.
I believe a lot of it does vacate and that causes 'bouncing' ballistics which do not help accuracy.