Although not Cherokee, another one that you might be interested in and try to find is the Seth Hill horn. I saved a photo and a sketch someone had made of the scrimshaw a few years ago from the internet, but the site no longer exists to give a link to. I think this horn might be shown in one of the newer powderhorn books?
He was a Mohawk, so north of your interest, but about the right timeframe you're looking at.
I don't know if he made or scrimshawed it, but he must have used it.
Engraved is "Seth Karenharegowagh His Powder Horn 177?"
(I can't read the last number on the date.)
There's a map of lake Erie and a small unlabled fort which i guess is Detroit, and an astarisc like symbol that's way to the east, maybe Ft. Niagara?
A stylised British coat of arms with a crowned lion to the left and a unicorn to the right, plants and flowers, a horse with a rider holding a curved sword, a spear in the other hand sticking into a dragon's mouth.
The horn has the "lobed" style shape at the big end's edge, with 2 holes for a strap and at the spout end area a grooved band.
The plug end has lots of domed round metal tacks apparently holding it in place.
I'm not sure if the tacks were originally on the horn when it was first made though or maybe added at a later time?
Art just made a great point about the first horn and i suppose possibly any native made object.
This Seth Hill horn i just was trying to describe was owned by a Mohawk and they did'nt aparently always get along with southern groups and i did'nt mean to suggest copying any symbols directly, in case they have a meaning we don't know. Just an example probably used by a Native American.
At the Frontierfolks forum there are several guys that study the Southeast, but ...
John