An interesting observation Daryl made. In every case (for me so far) the higher the charge, the higher the poi. Example: in my .45 I use a target/general load of 53grns of 3f and it hits point of aim, for me, at 50yds. Loaded with my deer load of 80grns it hits a good 2" and change high at 50yds. 40grns puts the ball low and out of sight below the bbl. When I sight in a new rifle I try to decide what my primary use will be. Then, I find a good, accurate, target/everyday load that hits point of aim and test to see how high the heaviest load I'll use will strike. With the .45 that means I aim a shade low on deer up to 75 yds or so. The target load still allows me to head shoot squirrels without using "Kentucky windage". This, at least, has been my experience.