I shot all kinds of combinations a few days ago. #6, #4, lots of powder, less powder, lots of shot and less shot. I even patched the shot but found it didn’t work worth a hoot in a jug choke.
Sometimes I weighed my components, sometimes I used a powder measure.
I noticed when I weighed my powder my pattern opened up a good bit so I checked my powder measure and found when it was set on 100 gr it was really throwing 85 with 1F.
My best patterns were with 85 gr of 1F and 1 ¼ oz of shot, 7 to the spine of a turkey target at 25 yards.