Tmas, I'm just an "average Joe shooter", I use my guns primarily for hunting and punching some paper for fun.
If you are looking at something to pop squirrels and shoot a bit of paper, I don't think you will find one profile or rifling style or even a barrel maker significantly (measurably) more accurate then another.
My "current line-up" of black powder rifles includes:
A 50 cal, 7/8" straight (Green Mountain), 36" long, 1:70 square rifled
A 45 cal, Southern Classic swamped (Rice), 42" long, 1:66 radius (round) rifled
A 40 cal, 13/16" straight (Colerain), 42" long, 1:48 radius (round) rifled
A 38 cal, 7/8"-3/4" tapered (FCI), 31" long, 1:48 radius (round) rifled.
So different twists, different profiles, and lengths varying from 31 to 42" long and I am NO Better or NO Worse a shot with any of them out to my (maximum) 75 yard "hunting range".
They will always be capable of shooting "better than I will". I will never shoot enough or spend enough time "getting good enough" that I would be able to answer your question - many of us are in the same boat
PS - I use the 38 cal for hunting Whitetails. Many would cringe at the thought (and I'm not advocating the use of - but in my style of hunting it's both ethical and lethal). Don't sell the 40 cal short - it worked just fine for Bambi, until Charles built me that fine 38 caliber barrel.