UA, there really is only the two areas (a third for some styles). The forward area for a front lock bolt , which you don't want and where the cock makes contact on the lock plate, the thick part,The thinner area below that would likey interfere with the mainspring. If you look at percussion rifles with one lock bolt, they are basically in the same spot as flint. You have some room forward and back, but not much. Your question on whether to drill and tap seemed odd.
On an Indians trade gun I copied, I put a third screw at the tail of the lockplate. Now that one will make you puckerup, on that rifle there was no margin of error, no room to come forward due to sear arm. Too close to either edge, there would have been distortion of lock plate edges when tapping threads. Some day I'll post a pic.