Years ago, guys around here used 110gr. 2F in a .50 and 120gr. 2F in a .54 for hunting - deer, elk, moose & bear. some used 120 in their .50's while others used up to 140 in their .54's and thought nothing of it - ie: normal hunting loads. Today, I see a trend towards what I consider squib loads for hunting - 65gr. in a .54 because even less in a handgun will kill a deer - "nothing more is needed" is the usual reason. Black Jaque - I don't see a problem with your load. With a good, accurate combination, it will be a hard hitting, flat shooting load.
Are we getting softer in or old age and look for reasons to drop what were normal charges? It even sees a rarity today to see someone using 100gr, yet that is not a heavy load for a .50. We used 110gr. 2F with 370 gr. Maxiballs in TC's in the early 70's - normal load. Yes, I know it's a lousy hunting bullet- didn't know that then.
Lets not forget the large game has large bones that stop squib loads. A .54 & descent load might have a chance after glancing on a leg bone, but a squib .50 doesn't.
oops - preaching again