I've only made about 10 guns over the last three years of decent to good quality, and, if there's any signature at all, it's bone.
If I learned one lesson with bone, it is to coat it with rubber cement when staining the gun. Once stain gets into bone, it goes so deep that it won't come out, and you can lose control of your final look very quickly.
I try to get all the bone to look like this...
paste image hostI judge it looks very nice as a thumbpiece, and always try to put one in my guns.
All I use, though, is the store bought blanks usually sold as knife scales. That stinks enough when being worked so I can't imagine boiling and cooking the pieces.
Wear a mask, too, because few things sand so fine as to get into the sinuses as bone...