I am prone to patching, however, did have fun with a patched ball on the powder, with 3 000 buck on top held by a card wad in my rifled .54 flint pistol.
The pattern at 12 yards was about 10" round, with the ball punching center (10ring) every time on the B-27 target, the buckshot perfectly radial around the centre hole. This
struck me as being a devastatingly effective defense round.
The patch will shoot more cleanly and probably more accurately, but then, the large bore English pistols & .54 US martial pistols, were favoured for running bison (from horseback) on the prairies. Technically, these were quite close range guns and wads would suffice for that, certainly. They, of course, were also fired at somewhat longer ranges during 'fights'.