Sorry I was so blunt.
Snapper was pretty much spot-on with his post.
A good conical (I would personally NEVER consider any sabot) in a flat-nosed hollow point pure lead 450 through 650gr. bullet of groove diameter, .45 for lighter, 50 through .54 for heavier
if used in a rifle I was very well familiar with, and had practiced extensively at 100 through 500yards in 50 yard intervals and had a sight that could be regulated for each of those
ranges - (yes, such a sight is available but has no place on an even remotely PC ML). I might consider such a shot, perhaps on a bedded bull - again- ranged with a laser unit, and good sights
calibrated for the range - it is possible, but
as oldtraveller noted, 2 steps with exactly the correct hold turns into a gut shot, shot through the hind legs, or hitting a cow, or one of a number of other
problems\errors - other elk, not seen at the time.
Who is spotting the shot - has to be out of the smoke, to positively tell if a hit & where it is hit, if it is a hit. ML 'bullet' when striking large game, usually makes no more than a slit that usually
does not bleed. High lung hit might not bleed for a 400yard run.
Usually an exit is necessary for any decent blood trail. I'm sorry, the requirements, as far as I'm concerned, are too strenuous for 98% of modern rifle shooters, let alone ML bullet shooters.
Round balls, in my opinion are totally out of the equation. All of this is rather elementary for me - stalk closer or don't shoot. Out to 150yards with a decent load and .54 or larger round ball, a
bullet shooting ML has absolutely no advantage.
I've seen that myself.