Absolutely, they did. Francis Selous used a shortened 4 bore Dutch Fouler for a while in securing ivory for the trade.
He wrote, after switching to nitro-express rounds, that he wished he'd "never shot that accursed 4 bore. It gave me a such a flinch
I could never shake it" (or words to that effect) he added about it ruining his accuracy for life due to the flinch.
So- well, it's up to you, Bill.
Selous had a "kaffir" loading it for him. 2 hands-full of powder (small hands, maybe?) & a round ball, of course.