Make them the same height above the centre of the bore to start.
The front sight might need a minor amount of filing to get it on.
Depends much on what range you want it sighted for.
Level will likely be close to dead on at 25 and maybe 1/2" high at50.
My .50 is a Rice Gun-maker's barrel. C-weight is a heavier one.
Taylor's .50 Rice on his Voluptuous Virginia is a C weight, I think.
Much also depends on how you see sights. It Taylor's rifle is zeroed at 50yards for him
it will shoot 2" low for me.