Double rifles are regulated so that both barrels shoot parallel to one another to infinity. When fired at a target, the bullets will strike side by side, never in the same hole. To do otherwise would render "express sights" as a fool's folly.
Also the ballistic coefficient of an elongated projectile changes during its flight. A roundball's does not. To make a roundball shoot farther and flatter, you slow down the twist and up the powder charge. Poor range estimation, and fixed sights make distance shooting impractical.
Double barreled round ball rifles 'should' be regulated to shoot parallel - as should all double rifles, fixed ammo or muzzleloading. They generally do this, if regulated correctly, with one load only and will cross or diverge with any other weight of charge or 'ball' weight.
Unfortunately, cheap well regulated guns are like frog hair. As well, properly regulated guns costing many thousands of dollars are like hen's teeth - few and far between. To properly regulate a set of barrels, the gun smith must shoot, separate then re-solder, shoot, separate and re-solder the barrels several or many times before he gets it right. No mass produced guns have proerly regulated barrels.
We get lucky sometimes and find a load that will put the barrels close enough together to be useful. As with mine, I would shoot the left barrel first(rear trigger), it being zeroed at 50 yards, while the right barrel is zero'd at 100. The groups run one over the other, a scenario fairly useful with practise.
Using a separate charge for each barrel, or as these Pedersoli guns are designed, a set of sights for each barrel - I don't agree with, but if having a gun that cannot be brought to shoot well, either is the only answer, I guess.
Forsyth spoke of moving the sight to split the difference, then learning where to hold for each barrel - this sort of thing has been done since the mid 1800's. Out of all the double muzzleloading guns Forsyth owned over the years, he'd only had a couple that actually shot parallel.
There are several different ball diameters that can be tried, along with different granulations of powder, along with different patch thicknesses and material make, along with a wide variety of powder charges- soemwhere in there, with experimentation, you might find a load that is useful - I did, on my first trip to the range with my double .58, fine tuning on the second trip. I xcan even shoot the black powder trail, making lefts and rights on all targets - quite impressive to see and do.
Knowing where to start helps. ie: ball at the most .015", better .010" to .005" under bore size and .015" to .025" patch thickness. The smaller the ball, the thicker the patch. If it's hard to load, you didn't re-crown the muzzles well enough. The big bores load easily with a heavy patch. Cloth of .010" to .012" is panty material for Canadian winters, it is not patch material for round balls ulless those balls are larger than the bore.
The crown needs to be addressed before going to the range - otherwise you are wasting powder and shot.