Lyman's data in their first black powder handbook, showed considerably lower pressures for 2F when loaded to the same velocities as produced by a given load of 3F. In other words, it took more 2F but produced less pressure at the same velocity as 3F.
Back in the 70's we found in rifles from .50 up, 2f produced better accuracy and LESS fouling than did 3F. This was likely due to the 3F's higher pressure being harder on the patches we were using.
I understand this 'phenomena' today, so I used even better patching that will work with both powders equally. So, in .36, .40. 45 and .50 and .69 rifles & the .62 smoothie, I developed accuracy loads for both 2F and 3F, producing similar velocities and the identical accuracy. Thus, no matter what powder I have in possession, I already have proven loads for any of my guns with THAT powder.