What I am saying with the big 'bore' rifles, is that the most accurate load for that rifle is also strong enough for the hunting load - for any game suitable for it's ball. If one makes the decision to shoot a load of less accuracy, as I do for close range shooting to 50yards with the 14 bore, one must put up with that inferior accuracy. On our large gong targets, there is lots of room for error, the little pine squirrel in the hoop, being the anomaly - it's a toughie.
That gun is actually a good example. It's light, close range load of 3 drams, ie: 82gr. 2F produces almost 1,200fps - speed of sound stuff. It's accuracy at 50 yards is 2" and 4" at 100 shooting off bags. It's accuracy load, also it's hunting load of 140gr. 2F, will put 5 consecutive shots under an inch at 50yards and 1" to 1 1/2" at 100 meters - again, single bag rest sitting at a bench & open sights. There are a lot of modern ctg. rifles out there won't do as well, even with a scope and handloads. So - the best accuracy, ie; target accuracy, is what we find when we keep testing by adjusting charges and changing components, ie: patch thickness/weave/material, powder granulation sizes, 3F, 2F 1F or ball sizes - over bore size, bore size, .005" under, .010" under - perhaps even smaller for really deep grooves that require VERY thick material or leather to fill, like sail canvas or buck skin. It's all in testing and not being satisfied with mediocre.