Been noted many times here that you can develop and perhaps should develop loads for all your rifles with both powder granulations.
I say this due to distinct possibility of having only one or the other 'in stock' at a given time and since you developed loads for both 2F and 3F in your .30 through .50's or .54's, no problem, use what you have.
By the same token, I have loads in both my .58 and .69, that allow me to use 3F, even though 2F is the normal powder I use in those rifles.
In my .40 and .45, I have to use 10gr. MORE 2F to get the same ballistics (velocity), poi and accuracy as with their normal 3f loads.
With the patch and ball combinations I use, 2F shoots just as cleanly as 3F.
I have yet to experiment with the .32, but 2F will work in it too, just have to find it's sweet spot with 2F. There is not magic - no hard and fast rule on what you HAVE to use in what calibre, just do it so you will know - record your results. I use 3 ring binders for recording load data.