When I do my patterns, I have my drawing on paper first. I pretend that the barrel is straight. That's the only way I can get things consistently straight and in order as far as drop at the butt, comb, etc. is concerned. In essence, everything is indexed off the centerline of the barrel, up and down.
Anyway, I transfer the drawing to a piece of luan (sometimes, if I think I'm going to do more than one of this same design), again, pretending that the barrel is straight, just to give me a good straight edge on the top parallel to the bore. I don't worry about figuring the fore end yet, I just get it roughly to shape and oversize, I just need something for proper positioning on the blank at this point. When I have the pattern where I want it, I trace it off, then measure down from the top-of-the-barrel line half the thickness of the barrel and make my centerline and then cut off this slab of wood to begin inletting the barrel. Once I get the barrel in, then I worry about the finer points of positioning the ramrod.
Normally, I do 1/8" between the rod and barrel at both the breech and the muzzle, but with some barrels that have relatively small muzzles, I will do more there. Generally, I want the rod to NOT be parallel with the bore, but ever so slightly tapered towards the muzzle...definitely never the other way though! Parralel is OK, depending upon just what barrel you're working with, but often, it makes the front end look too thick. I guess it depends upon just what you're doing. Some rifles should done with very straight fore ends, whereas others (primarliy earlier ones) can have taper in the fore end.
I draw it out on the blank, basically drawing the fore end around where the rod goes, and then just cut it out and drill it. I make sure that my pattern for the butt is still right in relation to the barrel, and adjust as necessary (I often inlet the barrel deeper than I need to, so I then need to move the butt pattern to compensate) and cut it out.