IMHO, Dane has it pretty well right, however, the question to patch/ball combinations depends on what you expect, in the way of accuracy. Do you want to shoot pinwheel Xs at 100 yards, or simply hit a 6" gong at 50 yards, or a deer at 40 yards? what level of difficulty in loading will you accept? Thumb start, vs repeatedly smacking a starter to get that patch/ball combo, into the bore. There are trade offs, no matter what you do.
IMHO, I would buy an assortment of balls ranging from about .005 undersize to .010, and .015 undersize, and .015 and .020 thick patching. One load, with a smaller ball or thinner patch, might load easily and work very well for plinking and hunting. Another, tighter, load might work better for match shooting.
To that end, I have gone to a .526 ball, in a .54 bore, with a .020 patch, that loads fairly easy, and shoots accurately enough for my needs.