I used to think it did not matter much.
I have been working with a 32 cal rifle that has wide lands and narrow grooves. This is opposite of what I think is best. IT causes major friction with a ball and patch combo that gives compression in the grooves.
I tired Jojoba, moose milk, spit and others. I had high hopes for jojoba. It is supposed to be close to sperm oil. With a 310 ball and a o.018 patch I had no luck. Jojoba is a poor lubricant, the balls loaded with great difficulty. They required several wacks with a steel rod, the wood rod was impossible. The steel rod got oily and gripping it was a problem. It was messy.
On a whim I tried a mix of venison tallow and about 10% anhydrous lanolin. I made strips of cloth and dunked them in melted lube, then rolled them up. This stuff is amazing. Loading effort is reduced 90%. I can easily load a .310 ball with a 0.025" denim patch. IT is clean to work with. The consistency is waxy, not goopy or oily. It shots really clean, I swabbed every five shots because I thought I should. NO fouling build up was noticeable. As an added bonus, cutting patches at the muzzle is easier for me than centering tiny patches and balls.
I need to work up some loads off the bench and see how it goes. I shot some respectable off hand groups at the monthly club shoot, that does not mean much though. Sometime a lube can be too slick. I hope the tighter combination with tighten things up on the target.
So, patch lubes are a cut and try thing.